Portal:Medicine
The Medicine Portal
Medicine is the science and practice of caring for patients, managing the diagnosis, prognosis, prevention, treatment, palliation of their injury or disease, and promoting their health. Medicine encompasses a variety of health care practices evolved to maintain and restore health by the prevention and treatment of illness. Contemporary medicine applies biomedical sciences, biomedical research, genetics, and medical technology to diagnose, treat, and prevent injury and disease, typically through pharmaceuticals or surgery, but also through therapies as diverse as psychotherapy, external splints and traction, medical devices, biologics, and ionizing radiation, amongst others.
Medicine has been practiced since prehistoric times, and for most of this time it was an art (an area of creativity and skill), frequently having connections to the religious and philosophical beliefs of local culture. For example, a medicine man would apply herbs and say prayers for healing, or an ancient philosopher and physician would apply bloodletting according to the theories of humorism. In recent centuries, since the advent of modern science, most medicine has become a combination of art and science (both basic and applied, under the umbrella of medical science). For example, while stitching technique for sutures is an art learned through practice, knowledge of what happens at the cellular and molecular level in the tissues being stitched arises through science.
Prescientific forms of medicine, now known as traditional medicine or folk medicine, remain commonly used in the absence of scientific medicine and are thus called alternative medicine. Alternative treatments outside of scientific medicine with ethical, safety and efficacy concerns are termed quackery. (Full article...)
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Featured articles are displayed here, which represent some of the best content on English Wikipedia.
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John Rolph (4 March 1793 – 19 October 1870) was a Canadian physician, lawyer, and political figure. As a politician, he was considered the leader of the Reform faction in the 1820s and helped plan the Upper Canada Rebellion. As a doctor, he founded several medical schools and incorporated new teaching techniques and medical procedures into his lectures. However, his actions against rival medical schools decreased public confidence in the ability of medical professionals to regulate themselves.
Rolph grew up in England and was educated in medicine and law. He immigrated to Upper Canada in 1813 and lived on his father's farm in Port Talbot, where he practiced law and medicine concurrently and opened a medical school called the Talbot Dispensary. In 1824, Rolph was elected to the Parliament of Upper Canada and returned to England to petition the Colonial Office to allow the naturalization of American citizens in Canada. He was elected as an alderman to Toronto's first city council, though he resigned after his council colleagues did not select him to be the city's mayor. (Full article...) -
Schizophrenia is a mental disorder characterized variously by hallucinations (typically, hearing voices), delusions, disorganized thinking and behavior, and flat or inappropriate affect. Symptoms develop gradually and typically begin during young adulthood and are never resolved. There is no objective diagnostic test; diagnosis is based on observed behavior, a psychiatric history that includes the person's reported experiences, and reports of others familiar with the person. For a diagnosis of schizophrenia, the described symptoms need to have been present for at least six months (according to the DSM-5) or one month (according to the ICD-11). Many people with schizophrenia have other mental disorders, especially mood, anxiety, obsessive-compulsive, and substance use disorders.
About 0.3% to 0.7% of people are diagnosed with schizophrenia during their lifetime. In 2017, there were an estimated 1.1 million new cases and in 2022 a total of 24 million cases globally. Males are more often affected and on average have an earlier onset than females. The causes of schizophrenia may include genetic and environmental factors. Genetic factors include a variety of common and rare genetic variants. Possible environmental factors include being raised in a city, childhood adversity, cannabis use during adolescence, infections, the age of a person's mother or father, and poor nutrition during pregnancy. (Full article...) -
Paul Nobuo Tatsuguchi (辰口 信夫, Tatsuguchi Nobuo), sometimes mistakenly referred to as Nebu Tatsuguchi (August 31, 1911 – May 30, 1943), was a Japanese soldier and surgeon who served in the Imperial Japanese Army (IJA) during World War II. He was killed during the Battle of Attu on Attu Island, Alaska, United States, on May 30, 1943.
A devout Seventh-day Adventist, Tatsuguchi studied medicine and was licensed as a physician in the United States (US). He returned to his native Japan to practice medicine at the Tokyo Adventist Sanitarium, where he received further medical training. In 1941, he was ordered to cease his medical practice and conscripted into the IJA as an acting medical officer, although he was given an enlisted rather than officer rank because of his American connections. In late 1942, Tatsuguchi was sent to Attu, which had been occupied by Japanese forces in June 1942. On May 11, 1943, The United States Army landed on the island, intending to retake American soil from the Japanese. (Full article...) -
Dementia with Lewy bodies (DLB) is a type of dementia characterized by changes in sleep, behavior, cognition, movement, and regulation of automatic bodily functions. Memory loss is not always an early symptom. The disease worsens over time and is usually diagnosed when cognitive impairment interferes with normal daily functioning. Together with Parkinson's disease dementia, DLB is one of the two Lewy body dementias. It is a common form of dementia, but the prevalence is not known accurately and many diagnoses are missed. The disease was first described on autopsy by Kenji Kosaka in 1976, and he named the condition several years later.
REM sleep behavior disorder (RBD)—in which people lose the muscle paralysis (atonia) that normally occurs during REM sleep and act out their dreams—is a core feature. RBD may appear years or decades before other symptoms. Other core features are visual hallucinations, marked fluctuations in attention or alertness, and parkinsonism (slowness of movement, trouble walking, or rigidity). A presumptive diagnosis can be made if several disease features or biomarkers are present; the diagnostic workup may include blood tests, neuropsychological tests, imaging, and sleep studies. A definitive diagnosis usually requires an autopsy. (Full article...) -
Fluoridation does not affect the appearance, taste or smell of drinking water.
Water fluoridation is the addition of fluoride to a public water supply to reduce tooth decay. Fluoridated water contains fluoride at a level that is effective for preventing cavities; this can occur naturally or by adding fluoride. Fluoridated water operates on tooth surfaces: in the mouth, it creates low levels of fluoride in saliva, which reduces the rate at which tooth enamel demineralizes and increases the rate at which it remineralizes in the early stages of cavities. Typically a fluoridated compound is added to drinking water, a process that in the U.S. costs an average of about $1.32 per person-year. Defluoridation is needed when the naturally occurring fluoride level exceeds recommended limits. In 2011, the World Health Organization suggested a level of fluoride from 0.5 to 1.5 mg/L (milligrams per litre), depending on climate, local environment, and other sources of fluoride.
In 2024, the Department of Health and Human Services' National Toxicology Program found that higher estimated fluoride exposures, such as drinking water fluoride concentrations exceeding the WHO guideline of 1.5 mg/L, are consistently associated with lower IQ in children. While the majority of studies were conducted in high-exposure areas, the findings underscore the potential for adverse effects on IQ and neurodevelopment when cumulative fluoride intake surpasses thresholds, whether from water or other sources. Recent U.S. court rulings have raised concerns about the potential health risks of water fluoridation, including findings by the EPA and new risk assessments that suggest the benefits may be waning. Bottled water typically has unknown fluoride levels. (Full article...) -
Race Against Time: Searching for Hope in AIDS-Ravaged Africa is a non-fiction book written by Stephen Lewis for the Massey Lectures. Lewis wrote it in early to mid-2005 and House of Anansi Press released it as a corresponding lecture series began in October 2005. Each of the book's chapters were delivered as a different lecture in a different Canadian city, beginning in Vancouver on October 18 and ending in Toronto on October 28. The speeches were aired on CBC Radio One between November 7 and 11. The author and orator, Stephen Lewis, was at that time the United Nations Special Envoy for HIV/AIDS in Africa and former Canadian ambassador to the United Nations. Although he wrote the book and lectures in his role as a concerned Canadian citizen, his criticism of the United Nations (UN), international organizations, and other diplomats, including naming specific people, was called undiplomatic and led several reviewers to speculate whether he would be removed from his UN position.
In the book and the lectures, Lewis argues that significant changes are required to meet the Millennium Development Goals in Africa by their 2015 deadline. Lewis explains the historical context of Africa since the 1980s, citing a succession of disastrous economic policies by international financial institutions that contributed to, rather than reduced, poverty. He connects the structural adjustment loans, with conditions of limited public spending on health and education infrastructure, to the uncontrolled spread of AIDS and subsequent food shortages as the disease infected much of the working-age population. Lewis also addresses such issues as discrimination against women and primary education for children. To help alleviate problems, he ends with potential solutions which mainly require increased funding by G8 countries to levels beyond what they promise. (Full article...) -
Lung cancer, also known as lung carcinoma, is a malignant tumor that begins in the lung. Lung cancer is caused by genetic damage to the DNA of cells in the airways, often caused by cigarette smoking or inhaling damaging chemicals. Damaged airway cells gain the ability to multiply unchecked, causing the growth of a tumor. Without treatment, tumors spread throughout the lung, damaging lung function. Eventually lung tumors metastasize, spreading to other parts of the body.
Early lung cancer often has no symptoms and can only be detected by medical imaging. As the cancer progresses, most people experience nonspecific respiratory problems: coughing, shortness of breath, or chest pain. Other symptoms depend on the location and size of the tumor. Those suspected of having lung cancer typically undergo a series of imaging tests to determine the location and extent of any tumors. Definitive diagnosis of lung cancer requires a biopsy of the suspected tumor be examined by a pathologist under a microscope. In addition to recognizing cancerous cells, a pathologist can classify the tumor according to the type of cells it originates from. Around 15% of cases are small-cell lung cancer (SCLC), and the remaining 85% (the non-small-cell lung cancers or NSCLC) are adenocarcinomas, squamous-cell carcinomas, and large-cell carcinomas. After diagnosis, further imaging and biopsies are done to determine the cancer's stage based on how far it has spread. (Full article...) -
Dengue fever is a mosquito-borne disease caused by dengue virus, prevalent in tropical and subtropical areas. It is frequently asymptomatic; if symptoms appear they typically begin 3 to 14 days after infection. These may include a high fever, headache, vomiting, muscle and joint pains, and a characteristic skin itching and skin rash. Recovery generally takes two to seven days. In a small proportion of cases, the disease develops into severe dengue (previously known as dengue hemorrhagic fever or dengue shock syndrome) with bleeding, low levels of blood platelets, blood plasma leakage, and dangerously low blood pressure.
Dengue virus has four confirmed serotypes; infection with one type usually gives lifelong immunity to that type, but only short-term immunity to the others. Subsequent infection with a different type increases the risk of severe complications. The symptoms of dengue resemble many other diseases including malaria, influenza, and Zika. Blood tests are available to confirm the diagnosis including detecting viral RNA, or antibodies to the virus. (Full article...) -
Leeches are segmented parasitic or predatory worms that comprise the subclass Hirudinea within the phylum Annelida. They are closely related to the oligochaetes, which include the earthworm, and like them have soft, muscular segmented bodies that can lengthen and contract. Both groups are hermaphrodites and have a clitellum, but leeches typically differ from the oligochaetes in having suckers at both ends and ring markings that do not correspond with their internal segmentation. The body is muscular and relatively solid; the coelom, the spacious body cavity found in other annelids, is reduced to small channels.
The majority of leeches live in freshwater habitats, while some species can be found in terrestrial or marine environments. The best-known species, such as the medicinal leech, Hirudo medicinalis, are hematophagous, attaching themselves to a host with a sucker and feeding on blood, having first secreted the peptide hirudin to prevent the blood from clotting. The jaws used to pierce the skin are replaced in other species by a proboscis which is pushed into the skin. A minority of leech species are predatory, mostly preying on small invertebrates. (Full article...) -
Thyrotoxic periodic paralysis (TPP) is a rare condition featuring attacks of muscle weakness in the presence of hyperthyroidism (overactivity of the thyroid gland). Hypokalemia (a decreased potassium level in the blood) is usually present during attacks. The condition may be life-threatening if weakness of the breathing muscles leads to respiratory failure, or if the low potassium levels lead to abnormal heart rhythms. If untreated, it is typically recurrent in nature.
The condition has been linked with genetic mutations in genes that code for certain ion channels that transport electrolytes (sodium and potassium) across cell membranes. The main ones are the L-type calcium channel α1-subunit and potassium inward rectifier 2.6; it is therefore classified as a channelopathy. The abnormality in the channel is thought to lead to shifts of potassium into cells, under conditions of high thyroxine (thyroid hormone) levels, usually with an additional precipitant. (Full article...) -
Prostate cancer is the uncontrolled growth of cells in the prostate, a gland in the male reproductive system below the bladder. Abnormal growth of prostate tissue is usually detected through screening tests, typically blood tests that check for prostate-specific antigen (PSA) levels. Those with high levels of PSA in their blood are at increased risk for developing prostate cancer. Diagnosis requires a biopsy of the prostate. If cancer is present, the pathologist assigns a Gleason score, and a higher score represents a more dangerous tumor. Medical imaging is performed to look for cancer that has spread outside the prostate. Based on the Gleason score, PSA levels, and imaging results, a cancer case is assigned a stage 1 to 4. A higher stage signifies a more advanced, more dangerous disease.
Most prostate tumors remain small and cause no health problems. These are managed with active surveillance, monitoring the tumor with regular tests to ensure it has not grown. Tumors more likely to be dangerous can be destroyed with radiation therapy or surgically removed by radical prostatectomy. Those whose cancer spreads beyond the prostate are treated with hormone therapy which reduces levels of the androgens (male sex hormones) that prostate cells need to survive. Eventually cancer cells can grow resistant to this treatment. This most-advanced stage of the disease, called castration-resistant prostate cancer, is treated with continued hormone therapy alongside the chemotherapy drug docetaxel. Some tumors metastasize (spread) to other areas of the body, particularly the bones and lymph nodes. There, tumors cause severe bone pain, leg weakness or paralysis, and eventually death. Prostate cancer prognosis depends on how far the cancer has spread at diagnosis. Most men diagnosed have tumors confined to the prostate; 99% of them survive more than 10 years from their diagnoses. Tumors that have metastasized to distant body sites are most dangerous, with five-year survival rates of 30–40%. (Full article...) -
The 1966 New York City smog was a major air-pollution episode and environmental disaster, coinciding with that year's Thanksgiving holiday weekend. Smog covered the city and its surrounding area from November 23 to 26, filling the city's air with damaging levels of several toxic pollutants. It was the third major smog in New York City, following events of similar scale in 1953 and 1963.
On November 23, a large mass of stagnant air over the East Coast trapped pollutants in the city's air. For three days, New York City was engulfed in dangerously high levels of carbon monoxide, sulfur dioxide, smoke, and haze. Pockets of air pollution pervaded the greater New York metropolitan area, including parts of New Jersey and Connecticut. By November 25, the smog became severe enough that regional leaders announced a "first-stage alert". During the alert, leaders of local and state governments asked residents and industry to take voluntary steps to minimize emissions. Health officials advised people with respiratory or heart conditions to remain indoors. The city shut off garbage incinerators, requiring massive hauling of garbage to landfills. A cold front dispersed the smog on November 26, and the alert ended. (Full article...) -
Buruli ulcer (/bəˈruːli/) is an infectious disease characterized by the development of painless open wounds. The disease is limited to certain areas of the world, most cases occurring in Sub-Saharan Africa and Australia. The first sign of infection is a small painless nodule or area of swelling, typically on the arms or legs. The nodule grows larger over days to weeks, eventually forming an open ulcer. Deep ulcers can cause scarring of muscles and tendons, resulting in permanent disability.
Buruli ulcer is caused by skin infection with bacteria called Mycobacterium ulcerans. The mechanism by which M. ulcerans is transmitted from the environment to humans is not known, but may involve the bite of an aquatic insect or the infection of open wounds. Once in the skin, M. ulcerans grows and releases the toxin mycolactone, which blocks the normal function of cells, resulting in tissue death and immune suppression at the site of the ulcer. (Full article...) -
Chagas disease, also known as American trypanosomiasis, is a tropical parasitic disease caused by Trypanosoma cruzi. It is spread mostly by insects in the subfamily Triatominae, known as "kissing bugs". The symptoms change over the course of the infection. In the early stage, symptoms are typically either not present or mild, and may include fever, swollen lymph nodes, headaches, or swelling at the site of the bite. After four to eight weeks, untreated individuals enter the chronic phase of disease, which in most cases does not result in further symptoms. Up to 45% of people with chronic infections develop heart disease 10–30 years after the initial illness, which can lead to heart failure. Digestive complications, including an enlarged esophagus or an enlarged colon, may also occur in up to 21% of people, and up to 10% of people may experience nerve damage.
T. cruzi is commonly spread to humans and other mammals by the kissing bug's bite wound and the bug's infected feces. The disease may also be spread through blood transfusion, organ transplantation, consuming food or drink contaminated with the parasites, and vertical transmission (from a mother to her baby). Diagnosis of early disease is by finding the parasite in the blood using a microscope or detecting its DNA by polymerase chain reaction. Chronic disease is diagnosed by finding antibodies for T. cruzi in the blood. (Full article...) -
Genetics is the study of genes, genetic variation, and heredity in organisms. It is an important branch in biology because heredity is vital to organisms' evolution. Gregor Mendel, a Moravian Augustinian friar working in the 19th century in Brno, was the first to study genetics scientifically. Mendel studied "trait inheritance", patterns in the way traits are handed down from parents to offspring over time. He observed that organisms (pea plants) inherit traits by way of discrete "units of inheritance". This term, still used today, is a somewhat ambiguous definition of what is referred to as a gene.
Trait inheritance and molecular inheritance mechanisms of genes are still primary principles of genetics in the 21st century, but modern genetics has expanded to study the function and behavior of genes. Gene structure and function, variation, and distribution are studied within the context of the cell, the organism (e.g. dominance), and within the context of a population. Genetics has given rise to a number of subfields, including molecular genetics, epigenetics, and population genetics. Organisms studied within the broad field span the domains of life (archaea, bacteria, and eukarya). (Full article...)
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Dame Albertine Louisa Winner DBE FRCP FFPH (4 March 1907 – 13 May 1988) was a British physician and medical administrator. After graduating from University College Hospital Medical School, Winner practised at the Elizabeth Garrett Anderson Hospital, the Mothers' Hospital in Clapton, and Maida Vale Hospital for Nervous Diseases.
During the Second World War, she enlisted in the Royal Army Medical Corps, where she later served as the consultant to the Auxiliary Territorial Service. After the war, Winner served in the Department of Health as its first female deputy chief medical officer. In later life, she worked with Cicely Saunders in forming the first modern hospice at St Christopher's Hospice in Sydenham, London. In 1967, Winner was appointed as Dame Commander of the Order of the British Empire (DBE). Winner was also elected as president of the Medical Women's Federation in 1971. She died on 13 May 1988 in London. (Full article...) -
Osteogenesis imperfecta (IPA: /ˌɒstioʊˈdʒɛnəsɪs ˌɪmpɜːrˈfɛktə/; OI), colloquially known as brittle bone disease, is a group of genetic disorders that all result in bones that break easily. The range of symptoms—on the skeleton as well as on the body's other organs—may be mild to severe. Symptoms found in various types of OI include whites of the eye (sclerae) that are blue instead, short stature, loose joints, hearing loss, breathing problems and problems with the teeth (dentinogenesis imperfecta). Potentially life-threatening complications, all of which become more common in more severe OI, include: tearing (dissection) of the major arteries, such as the aorta; pulmonary valve insufficiency secondary to distortion of the ribcage; and basilar invagination.
The underlying mechanism is usually a problem with connective tissue due to a lack of, or poorly formed, type I collagen. In more than 90% of cases, OI occurs due to mutations in the COL1A1 or COL1A2 genes. These mutations may be hereditary in an autosomal dominant manner but may also occur spontaneously (de novo). There are four clinically defined types: type I, the least severe; type IV, moderately severe; type III, severe and progressively deforming; and type II, perinatally lethal. As of September 2021[update], 19 different genes are known to cause the 21 documented genetically defined types of OI, many of which are extremely rare and have only been documented in a few individuals. Diagnosis is often based on symptoms and may be confirmed by collagen biopsy or DNA sequencing. (Full article...) -
The heart is a muscular organ found in humans and other animals. This organ pumps blood through the blood vessels. Heart and blood vessels together make the circulatory system. The pumped blood carries oxygen and nutrients to the tissue, while carrying metabolic waste such as carbon dioxide to the lungs. In humans, the heart is approximately the size of a closed fist and is located between the lungs, in the middle compartment of the chest, called the mediastinum.
In humans, the heart is divided into four chambers: upper left and right atria and lower left and right ventricles. Commonly, the right atrium and ventricle are referred together as the right heart and their left counterparts as the left heart. In a healthy heart, blood flows one way through the heart due to heart valves, which prevent backflow. The heart is enclosed in a protective sac, the pericardium, which also contains a small amount of fluid. The wall of the heart is made up of three layers: epicardium, myocardium, and endocardium. (Full article...) -
Tuberculosis (TB), also known colloquially as the "white death", or historically as consumption, is a contagious disease usually caused by Mycobacterium tuberculosis (MTB) bacteria. Tuberculosis generally affects the lungs, but it can also affect other parts of the body. Most infections show no symptoms, in which case it is known as latent tuberculosis. Around 10% of latent infections progress to active disease that, if left untreated, kill about half of those affected. Typical symptoms of active TB are chronic cough with blood-containing mucus, fever, night sweats, and weight loss. Infection of other organs can cause a wide range of symptoms.
Tuberculosis is spread from one person to the next through the air when people who have active TB in their lungs cough, spit, speak, or sneeze. People with latent TB do not spread the disease. Active infection occurs more often in people with HIV/AIDS and in those who smoke. Diagnosis of active TB is based on chest X-rays, as well as microscopic examination and culture of bodily fluids. Diagnosis of latent TB relies on the tuberculin skin test (TST) or blood tests. (Full article...) -
Lambert–Eaton myasthenic syndrome (LEMS) is a rare autoimmune disorder characterized by muscle weakness of the limbs. It is also known as myasthenic syndrome, Eaton–Lambert syndrome, and when related to cancer, carcinomatous myopathy.
Around 60% of those with LEMS have an underlying malignancy, most commonly small-cell lung cancer; it is therefore regarded as a paraneoplastic syndrome (a condition that arises as a result of cancer elsewhere in the body). It is the result of antibodies against presynaptic voltage-gated calcium channels, and likely other nerve terminal proteins, in the neuromuscular junction (the connection between nerves and the muscle that they supply). The diagnosis is usually confirmed with electromyography and blood tests; these also distinguish it from myasthenia gravis, a related autoimmune neuromuscular disease. (Full article...) -
Elmer Ernest (E. E.) Southard (July 28, 1876 – February 8, 1920) was an American neuropsychiatrist, neuropathologist, professor and author. Born in Boston, Massachusetts, Southard lived in the city for nearly his entire life. He attended Boston Latin School and completed his education at Harvard University. At Harvard, Southard distinguished himself as a chess player. After briefly studying in Germany, he returned to the United States as a pathologist at Danvers State Hospital. Southard held academic appointments at Harvard University and its medical school.
He headed the Boston Psychopathic Hospital when it opened in 1912, pioneering the study of brain pathology with particular interests in shell shock and schizophrenia. Southard published several books, including Shell Shock and Other Neuropsychiatric Problems with nearly 1,000 case histories. He was president of the American Medico-Psychological Association and the Boston Society of Psychiatry and Neurology, and held advisory positions with the U.S. Chemical Warfare Service and the Eugenics Record Office. (Full article...) -
Sickles's leg bones on display
The amputated right lower leg of Union Army general Daniel Sickles, lost after a cannonball wound suffered at the Battle of Gettysburg on July 2, 1863, is displayed at the National Museum of Health and Medicine.
Sickles was a former New York politician who entered the army after the outbreak of the American Civil War in 1861. After originally commanding the Excelsior Brigade, Sickles was promoted to major general in 1862 and later commanded the III Corps at the battles of Chancellorsville and Gettysburg. At Gettysburg, Sickles moved the III Corps forward from his assigned position, and it was shattered by a Confederate attack. During the fighting, he was struck in the leg by a solid shot; the wound later required amputation above the knee. After the amputation, the limb was donated to the Army Medical Museum (now the National Museum of Health and Medicine), where it was used as a teaching example of battlefield trauma. Sickles sometimes visited the limb afterwards, and it remains a popular attraction at the museum. (Full article...) -
Toothaches, also known as dental pain or tooth pain, is pain in the teeth or their supporting structures, caused by dental diseases or pain referred to the teeth by non-dental diseases. When severe it may impact sleep, eating, and other daily activities.
Common causes include inflammation of the pulp, (usually in response to tooth decay, dental trauma, or other factors), dentin hypersensitivity, apical periodontitis (inflammation of the periodontal ligament and alveolar bone around the root apex), dental abscesses (localized collections of pus), alveolar osteitis ("dry socket", a possible complication of tooth extraction), acute necrotizing ulcerative gingivitis (a gum infection), and temporomandibular disorder. (Full article...) -
Wilson's disease (also called hepatolenticular degeneration) is a genetic disorder characterized by the excess build-up of copper in the body. Symptoms are typically related to the brain and liver. Liver-related symptoms include vomiting, weakness, fluid build-up in the abdomen, swelling of the legs, yellowish skin, and itchiness. Brain-related symptoms include tremors, muscle stiffness, trouble in speaking, personality changes, anxiety, and psychosis.
Wilson's disease is caused by a mutation in the Wilson disease protein (ATP7B) gene. This protein transports excess copper into bile, where it is excreted in waste products. The condition is autosomal recessive; for people to be affected, they must inherit a mutated copy of the gene from both parents. Diagnosis may be difficult and often involves a combination of blood tests, urine tests, and a liver biopsy. Genetic testing may be used to screen family members of those affected. (Full article...) -
Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by executive dysfunction occasioning symptoms of inattention, hyperactivity, impulsivity and emotional dysregulation that are excessive and pervasive, impairing in multiple contexts, and developmentally-inappropriate.
ADHD symptoms arise from executive dysfunction, and emotional dysregulation is often considered a core symptom. Impairments resulting from deficits in self-regulation such as time management, inhibition, and sustained attention can include poor professional performance, relationship difficulties, and numerous health risks, collectively predisposing to a diminished quality of life and a direct average reduction in life expectancy of 13 years. The disorder costs society hundreds of billions of US dollars each year, worldwide. It is associated with other neurodevelopmental and mental disorders as well as non-psychiatric disorders, which can cause additional impairment. (Full article...) -
Hypertension, also known as high blood pressure, is a long-term medical condition in which the blood pressure in the arteries is persistently elevated. High blood pressure usually does not cause symptoms itself. It is, however, a major risk factor for stroke, coronary artery disease, heart failure, atrial fibrillation, peripheral arterial disease, vision loss, chronic kidney disease, and dementia. Hypertension is a major cause of premature death worldwide.
High blood pressure is classified as primary (essential) hypertension or secondary hypertension. About 90–95% of cases are primary, defined as high blood pressure due to nonspecific lifestyle and genetic factors. Lifestyle factors that increase the risk include excess salt in the diet, excess body weight, smoking, physical inactivity and alcohol use. The remaining 5–10% of cases are categorized as secondary hypertension, defined as high blood pressure due to a clearly identifiable cause, such as chronic kidney disease, narrowing of the kidney arteries, an endocrine disorder, or the use of birth control pills. (Full article...) -
Rumination syndrome, or merycism, is a chronic motility disorder characterized by effortless regurgitation of most meals following consumption, due to the involuntary contraction of the muscles around the abdomen. There is no retching, nausea, heartburn, odour, or abdominal pain associated with the regurgitation as there is with typical vomiting, and the regurgitated food is undigested. The disorder has been historically documented as affecting only infants, young children, and people with cognitive disabilities (the prevalence is as high as 10% in institutionalized patients with various mental disabilities).
It is increasingly being diagnosed in a greater number of otherwise healthy adolescents and adults, though there is a lack of awareness of the condition by doctors, patients, and the general public.
Rumination syndrome presents itself in a variety of ways, with especially high contrast existing between the presentation of the typical adult patient without a mental disability and the presentation of an adult with a mental disability. Like related gastrointestinal disorders, rumination can adversely affect normal functioning and the social lives of individuals. It has been linked with depression. (Full article...) -
Enriqueta Medellín (10 December 1948 – 6 January 2022) was a Mexican surgeon and environmentalist. Raised in Mexico City, from a young age she participated in projects to clean up the city and became interested in the links between disease and the environment. She earned a degree as a medical surgeon from the National Autonomous University of Mexico and specialized in human genetics. She also studied environmental education and management.
After participating in humanitarian aid projects following the 1985 Mexico City earthquake, she and her extended family relocated to Aguascalientes City in 1987, where she worked as a surgeon while becoming known for environmental activism. Along with her mother and other activists, she founded the association Conciencia Ecológica (Ecological Consciousness) in 1992. This group of activists carried out the first recycling project in the state and introduced numerous projects to raise awareness on waste, teach people about preserving the environment, and protest against developmental projects that caused harm to the environment. She was involved at the local, state, national, and international levels in the creation of policy to protect ecosystems. (Full article...) -
The Xinxiu bencao (Chinese: 新修本草; pinyin: Xīnxiū běncǎo), also known as the Tang bencao (Chinese: 唐本草; pinyin: Táng běncǎo), is a Chinese pharmacopoeia written in the Tang dynasty by a team of officials and physicians headed by editor-in-chief Su Jing. It borrowed heavily from—and expanded upon—the earlier Bencao jing jizhu by Tao Hongjing. The text was first published in 659; although it is now considered lost in China, at least one copy exists in Japan, where the text had been transmitted to in 721. (Full article...)
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William Bronston (born March 1939) is an American physician and activist known for his involvement in the deinstitutionalization of Willowbrook State School in the early 1970s. Born in Los Angeles, Bronston graduated from the University of California, Los Angeles and the USC School of Medicine. At USC, he was a prominent student activist, organizing social and political public health projects and co-founding the New Left Student Health Organization. After graduating from USC in 1965, Bronston began his residency at the Menninger School of Psychiatry in Kansas, but was expelled from the institution after leading a sit-in for improvements in wages and working conditions for direct support professionals.
After his expulsion in 1968, Bronston moved to New York City where he briefly worked at a Black Panther Party medical clinic before leaving to become a staff physician at Willowbrook State School, a state institution for children with intellectual disabilities. At Willowbrook, Bronston quickly became critical of the institution's leadership and standards, clashing with Jack Hammond, the institute's director. In 1971, Bronston went public with his grievances and organized a movement to reform the institution, which culminated in a 1975 court decision deinstitutionalizing the school. Afterwards, Bronston returned to California, where he became the medical director of the Department of Developmental Disabilities at the California Department of Health and later at the California Department of Rehabilitation. (Full article...)
Did you know –
- ... that the McMurray test is part of the knee examination in case of suspected tears of the meniscus (pictured)?
- ... that Stauffer syndrome is paraneoplastic liver dysfunction due to renal cell carcinoma?
- ... that periodic fever syndromes or autoinflammatory syndromes include familial Mediterranean fever, hyperimmunoglobulinemia D with recurrent fever, TNF receptor associated periodic syndrome, Muckle–Wells syndrome, familial cold urticaria and periodic fever, aphthous stomatitis, pharyngitis and adenitis, among others?
General images –
The following are images from various Medicine-related articles on Wikipedia.
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A Ukrainian monument to the HIV pandemic (from History of medicine) -
Sometimes traditional medicines include parts of endangered species, such as the slow loris in Southeast Asia. (from Traditional medicine) -
Botánicas such as this one in Jamaica Plain, Boston, cater to the Latino community and sell folk medicine alongside statues of saints, candles decorated with prayers, lucky bamboo, and other items. (from Traditional medicine) -
Medicine during the First World War - medical transport (from History of medicine) -
Emil Kraepelin (1856–1926), the founder of modern scientific psychiatry, psychopharmacology and psychiatric genetics (from History of medicine) -
A doctor checks a patient's pulse in Meiji-era Japan. (from History of medicine) -
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A cuneiform terracotta tablet describing a medicinal recipe for poisoning (c. 18th century BCE). Discovered in Nippur, Iraq. -
"Diagram of the causes of mortality in the army in the East" by Florence Nightingale (from History of medicine) -
Ethical prayer for medical wisdom by Dr Edmond Fernandes (from Medical ethics) -
Life expectancy vs healthcare spending of rich OECD countries. US average of $10,447 in 2018. (from Health care) -
Jackson Memorial Hospital in Miami, the primary teaching hospital of the University of Miami's Miller School of Medicine and the largest hospital in the United States with 1,547 beds (from Health care) -
Most countries have seen a tremendous increase in life expectancy since 1945. However, in southern Africa, the HIV epidemic beginning around 1990 has eroded national health. (from History of medicine) -
Guy's Hospital in 1820 (from History of medicine) -
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Statue of Robert Koch, father of medical bacteriology, at Robert-Koch-Platz (Robert Koch square) in Berlin (from History of medicine) -
Galen (129–216 CE), known for his wide insights into anatomy (from History of medicine) -
Life Expectancy of the total population at birth among several OECD member nations. Data source: OECD's iLibrary (from Health insurance) -
A Neo-Assyrian cuneiform tablet fragment describing medical text (c. 9th to 7th century BCE) (from History of medicine) -
Primary care may be provided in community health centers. (from Health care) -
Hippocrates (c. 460–370 BCE). Known as the "father of medicine". (from History of medicine) -
Total healthcare cost per person. Public and private spending. US dollars PPP. For example: $6,319 for Canada in 2022. $12,555 for the US in 2022. (from Health care) -
Sketch of Muslim physician Muhammad ibn Zakariya al-Razi (from History of medicine) -
Medical personnel place sterilized covers on the arms of the daVinci Xi surgical system, a minimally-invasive robotic surgery system, at the William Beaumont Army Medical Center. (from History of medicine) -
18th-century medical remedies collected by a British Gentry family (from History of medicine) -
Smallpox vaccination in Niger, 1969. A decade later, this was the first infectious disease to be eradicated. (from History of medicine) -
![Image 27Global concentrations of health care resources, as depicted by the number of physicians per 10,000 individuals, by country. Data is sourced from a World Health Statistics 2010, a WHO report.[needs update] (from Health care)](//upload.wikimedia.org/wikipedia/commons/thumb/1/1f/Global_physician_density_map_-_WHO_2010.png/120px-Global_physician_density_map_-_WHO_2010.png)
Global concentrations of health care resources, as depicted by the number of physicians per 10,000 individuals, by country. Data is sourced from a World Health Statistics 2010, a WHO report.[needs update] (from Health care) -
Depiction of smallpox in Franciscan Bernardino de Sahagún's history of the conquest of Mexico, Book XII of the Florentine Codex, from the defeated Aztecs' point of view (from History of medicine) -
The Quaker-run York Retreat, founded in 1796, gained international prominence as a centre for moral treatment and a model of asylum reform following the publication of Samuel Tuke's Description of the Retreat (1813). (from History of medicine) -
Health Expenditure per capita (in PPP-adjusted US$) among several OECD member nations. Data source: OECD's iLibrary (from Health insurance) -
Seven named physicians and botanists of the Classical world from Vienna Dioscurides. Clockwise from top center: Galen, Dioscorides, Nicander, Rufus of Ephesus, Andreas of Carystus, Apollonius Mus or of Pergamon, Crateuas (from History of medicine) -
Curandera performing a limpieza in Cuenca, Ecuador (from Traditional medicine) -
The emergency room is often a frontline venue for the delivery of primary medical care. (from Health care) -
Infographic showing how healthcare data flows within the billing process (from Medical billing) -
Mandrake (written 'ΜΑΝΔΡΑΓΟΡΑ' in Greek capitals). Naples Dioscurides, 7th century (from History of medicine) -
A 12th-century manuscript of the Hippocratic Oath in Greek, one of the most famous aspects of classical medicine that carried into later eras (from History of medicine) -
"More Doctors Smoke Camels than Any Other Cigarette" advertisement for Camel cigarettes in the 1940s (from Medical ethics) -
The plinthios brochos as described by Greek physician Heraklas, a sling for binding a fractured jaw. These writings were preserved in one of Oribasius' collections. (from History of medicine) -
The numbers of Americans lacking health insurance and the uninsured rate from 1987 to 2008 (from Health insurance) -
COVID-19 swab testing in Rwanda (2021) (from History of medicine) -
healthcare expenditure in Japan by age group (from Health insurance) -
Health expenditure funding types (from Health insurance) -
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National Hospital for Neurology and Neurosurgery in London, United Kingdom is a specialist neurological hospital. (from Health care) -
American combat surgery during the Pacific War, 1943 (from History of medicine) -
Health spending by country. Percent of GDP (Gross domestic product). For example: 11.2% for Canada in 2022. 16.6% for the United States in 2022. (from Health care) -
Yarrow, a medicinal plant found in human-occupied caves in the Upper Palaeolithic period (from History of medicine) -
Mexico City epidemic of 1737, with elites calling on the Virgin of Guadalupe (from History of medicine) -
Zhang Zhongjing – a Chinese pharmacologist, physician, inventor, and writer of the Eastern Han dynasty (from History of medicine) -
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Patient, Surrey County Lunatic Asylum, c. 1850–58. The asylum population in England and Wales rose from 1,027 in 1827 to 74,004 in 1900. (from History of medicine) -
An American billing clerk preparing a detailed invoice. (1992) (from Medical billing) -
The Edwin Smith Surgical Papyrus, written in the 17th century BCE, contains the earliest recorded reference to the brain. New York Academy of Medicine. (from History of medicine) -
Taoist symbol of Yin and Yang (from Medical ethics) -
A cochlear implant is a common kind of neural prosthesis, a device replacing part of the human nervous system. (from History of medicine) -
AMA Code of Medical Ethics (from Medical ethics) -
Charite in Berlin (from History of medicine) -
Magical stela or cippus of Horus inscribed with healing encantations (c. 332 to 280 BCE) (from History of medicine)
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![Image 27Global concentrations of health care resources, as depicted by the number of physicians per 10,000 individuals, by country. Data is sourced from a World Health Statistics 2010, a WHO report.[needs update] (from Health care)](/wiki/File:Global_physician_density_map_-_WHO_2010.png)
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